Practice Contact Information
Tomsk Cancer Research Institute
5 Kooperativny Street
Tomsk
Tomsk region
634009
Russian Federation
Phone: +79069555289
Email: [email protected]
Web Site: https://onco.tnimc.ru/en/
Areas of surgical specialization
Endocrine Surgery, Head and Neck Surgeon, Reconstructive Head & Neck Surgery
Biography/Statement
M.D., Ph.D., D.Sc., Senior Researcher, Department of Head and Neck Tumors, Cancer Research Institute, Tomsk National Research Medical Center.
Denis E. Kulbakin graduated with honors from Siberian Medical University in 2008. From 2008 to 2010 he completed a residency training at the Head and Neck Cancer Department of the Cancer Research Institute of the Tomsk Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences (currently Cancer Research Institute of Tomsk NRMS). In 2013, he defended a doctoral thesis titled «Organ-preserving surgery after radical radiation therapy in patients with recurrent laryngeal cancer» for a Ph.D. degree. From 2016 to 2017, Dr. Kulbakin completed an internship in surgery at the Siberian State Medical University of the Ministry of Health of the Russian Federation. Since 2015, he has been a Senior Researcher at the Department of Head and Neck Cancer of Cancer Research Institute of Tomsk NRMS. In 2021, Dr. Kulbakin defended a doctoral thesis titled “Reconstructive surgery in the combined modality treatment of patients with head and neck tumors. Improving the technique, researching new reconstructive materials” for a D.Sc. degree.
Clinical Trials
Organ-preserving surgery for head and neck tumors using microsurgical reconstruction
Thyroidectomy and parathyroidectomy
Transoral laser microsurgery
Development of new implants for reconstructive surgery in the maxillofacial region.
Bibliography
Spirina Liudmila V. Expression of vascular endothelial growth factor and transcription factors HIF-1, NF-kB expression in squamous cell carcinoma of head and neck; association with proteasome and calpain activities / Spirina Liudmila V., Kondakova Irina V., Choynzonov Evgeny L., Chigevskaya Svetlana Y., Shishkin Dmitry A., Kulbakin Denis E. // J Cancer Res Clin Oncol (2013) 139:625–633
Мukhamedov Мarat. Organ-saving Surgery with the Use of TiNi-based Endografts in Larynx Cancer Patients / Мukhamedov Мarat, Kulbakin Denis, Gynter Victor, Choinzonov Еvgeniy, Checalkin Timofey, Hodorenko // Journal of Surgical Oncology Vol. 111 (2015) pp 231–236.
Choinzonov Еvgeniy. Organ-Preserving Surgery using Endografts from Superelastic Titanium-Nickelid-Based Alloy for Patients with Laryngeal Cancer / Choinzonov Еvgeniy, Мukhamedov Мarat, Kulbakin Denis, Buldakov Mikhail, Gynter Victor // Advanced Materials Research Vol. 1085 (2015) pp 414-418
Denis Kulbakin. Sparing Surgery for the Successful Treatment of Thyroid Papillary Carcinoma Invading the Trachea: A Case Report / Denis Kulbakin, Timofey Chekalkin, Marat Muhamedov, Evgeniy Choynzonov, Ji-hoon Kang, Seung-baik Kang, Victor Gunthera // Case Rep Oncol 2016;9:772–780. IF – 0,93
Kulbakin Denis. Thyroid Carcinosarcoma // American Journal of Biomedical Science & Research. – 2019. – 5(2). – P. 115-117.
Chernov V.I., Choynzonov E.L., Kulbakin D.E., Obkhodskaya E.V., Obkhodskiy A.V., Popov A.S., Sachkova A.S. and Sachkov V.I. Cancer Diagnosis by Neural Network Analysis of Data from Semiconductor Sensors // Diagnostics 2020, 10(9), 677; https://doi.org/10.3390/diagnostics10090677;
Vladimir I. Chernov, Evgeniy L. Choynzonov, Denis E. Kulbakin, Ekaterina N. Menkova, Elena V. Obkhodskaya, Artem V. Obkhodskiy, Aleksandr S. Popov, Evgeniy O. Rodionov , Victor I. Sachkov, Anna S. Sachkova. Non-Invasive Diagnosis of Malignancies Based on the Analysis of Markers in Exhaled Air. Diagnostics 2020, 10, 934; doi:10.3390/diagnostics10110934
Characterization and Determination of the Biocompatibility of Porous Polytetrafluoroethylene Membranes Fabricated via Electrospinning / I. Kolesnik, T. Tverdokhlebova, N. Danilenko, E. Plotnikov, D. Kulbakin, A. Zheravin, V. Bouznik, E. Bolbasov // Journal of Fluorine Chemistry. – June 2021. – Vol. 246, N 109798.
Solution blow spinning of PLLA/Hydroxyapatite composite scaffolds for bone tissue engineering / Arnold Popkov, Denis Kulbakin, Dmitry Popkov, Elena Gorbach, Natalia Kononovich, Nadezhda Danilenko, Ksenia Stankevich, Evgeny Choynzonov, Alexander Zheravin, Igor Khlusov, Ludmila Bondar, Vladimir Perelmuter, Evgeny Bolbasov, Sergei Tverdokhlebov // Biomedical Materials. – 2021. – Jul 20. – Vol. 16, N 5. – doi: 10.1088/1748-605X/ac11ca
E.S. Kolegova, M. R. Patysheva, I. V. Larionova, I. K. Fedorova, D. E. Kulbakin, E. L. Choinzonov, E. V. Denisov: Early-onset oral cancer as a clinical entity: aetiology and pathogenesis. Int. J. Oral Maxillofac. Surg. 2022; 51: 1497–1509. https://doi.org/10.1016/j.ijom.2022.04.005
Anna I. Kozelskaya, Sven Rutkowski, Johannes Frueh, Aleksey S. Gogolev, Sergei G. Chistyakov, Sergey V. Gnedenkov, Sergey L. Sinebryukhov, Andreas Frueh, Vladimir S. Egorkin, Evgeny L. Choynzonov, Mikhail Buldakov, Denis E. Kulbakin, Evgeny N. Bolbasov, Anton P. Gryaznov, Ksenia N. Verzunova, Margarita D. Apostolova and Sergei I. Tverdokhlebov. Surface Modification of Additively Fabricated Titanium-Based Implants by Means of Bioactive Micro-Arc Oxidation Coatings for Bone Replacement. J. Funct. Biomater. 2022, 13, 285. https://doi.org/10.3390/ jfb13040285
I.K. Fedorova, D.E. Kulbakin, E.S. Kolegova, M.R. Patysheva, E.V. Denisov, E.L. Choinzonov, A.P. Polyakov, A.V. Mordovsky, I.V. Rebrikova, A.D. Kaprin, D.A. Averinskaya, M.E. Romanova, P.A. Shatalov, P.V. Shegay, D.S. Kudashkina, L.P. Yakovleva, A.S. Vyalov, M.A. Kropotov, V.T. Tsiklauri, O.A. Saprina, N.S. Sukortseva, S.I. Samoilova, I.V. Reshetov. Treatment of young adults with oral cancer: current state and outlook (The Consortium «Etiology and pathogenesis of oral cancer in young adults»). Part 1. Head and neck. Russian Journal. 2022;10(4):83–91
Vorob’ev, A.O., Kul’bakin, D.E., Chistyakov, S.G.. Mitrichenko A. D., Dubinenko G. E., Akimchenko I. O., Plotnikov E. V., Gogolev A. S., Choinzonov E. L., Buznik V. M., Bol’basov E. N. Individual 3D-Printed Implants Made from a Copolymer of Vinylidene Fluoride with Tetrafluoroethylene: Studies of the Effects of Steam Sterilization on Structure and Toxicity. Biomedical Engineering. 2023; 57: 52–56. – DOI: 10.1007/s10527-023-10266-y
Naumov S.S., Kulbakin D.E., Krakhmal N.V., Vtorushin S.V. Molecular and biological factors in the prognosis of head and neck squamous cell cancer. Molecular Biology Reports. 2023: Jul 26. – DOI: 10.1007/s11033-023-08611-1 – URL: https://link.springer.com/article/10.1007/s11033-023-08611-1 – PMID: 37493876.