American Head & Neck Society

Advancing Education, Research, and Quality of Care for the Head and Neck oncology patient.

Published on by Geoffrey Young

Geoffrey Young – Miami, Florida

Practice Contact Information

Chief of Head and Neck Surgery, Miami Cancer Institute
8900 N Kendall Dr.

Miami
Florida
33176
United States

Phone: 7865962000
Email: [email protected]
Web Site: https://baptisthealth.net/en/health-services/cancer-services/pages/cancer-care/adult-cancers/head-neck-cancers.aspx

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon

Biography/Statement

Dr. Young is an international leader in the field of head and neck surgical oncology.  He  specializes in minimally invasive, robotic and complex open surgery for both cancer and benign head and neck tumors.  He also an expert in the field of melanoma and other head and neck skin cancers. Dr. Young has authored numerous scientific articles and has been an invited speaker at national and international  meetings. His research interests include individualized medicine and surgical innovations for the management of head and neck  malignancies.

Clinical Trials

As part of the Memorial Sloane Kettering Alliance, Miami Cancer Institute has access to numerous clinical trials

Bibliography

Selected Bibliography
Peer-reviewed Articles
1. Young GD, Winokur TS, Cerfolio RJ, Van Tine BA, Chow LT, Okoh V, Garver RI Jr. Differential expression and biodistribution of cytokeratin 18 and desmoplakins in non-small cell lung carcinoma subtypes. Lung Cancer. 2002 May; 36(2):133-41. PMID:11955647

 
2. Okoh V, Young GD, Winokur TS, Garver RI Jr. A novel assay for the quantification of invasion from raft cultures of lung carcinomas. Clin Exp Metastasis. 2004; 21(1):1-6. PMID:15065596

 
3. Rosenthal E, McCrory A, Talbert M, Young G, Murphy-Ullrich J, Gladson C. Elevated expression of TGF-beta1 in head and neck cancer-associated fibroblasts. Mol Carcinog. 2004 Jun; 40(2):116-21. PMID:15170816   DOI:10.1002/mc.20024

 
4. Young GD, Murphy-Ullrich JE. Molecular interactions that confer latency to transforming growth factor-beta. J Biol Chem. 2004 Sep 3; 279(36):38032-9. Epub 2004 Jun 18. PMID:15208302   DOI:10.1074/jbc.M405658200

 
5. Young GD, Murphy-Ullrich JE. The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-beta complex. J Biol Chem. 2004 Nov 12; 279(46):47633-42. Epub 2004 Sep 01. PMID:15342643   DOI:10.1074/jbc.M404918200

 
6. Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med. 2012 Mar 28; 4(127):127ra37. PMID:22461641   PMCID:3568523   DOI:10.1126/scitranslmed.3003689

 
7. Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM, Pai SI. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res. 2013 Mar 15; 73(6):1733-41. Epub 2013 Jan 03. PMID:23288508   PMCID:3602406   DOI:10.1158/0008-5472.CAN-12-2384

 
8. Taube JM, Young GD, McMiller TL, Chen S, Salas JT, Pritchard TS, Xu H, Meeker AK, Fan J, Cheadle C, Berger AE, Pardoll DM, Topalian SL. Differential expression of immune-regulatory genes associated with PD-L1 display in melanoma: Implications for PD-1 pathway blockade. Clin Cancer Res. 2015; 21(17):3969-76. PMID:25944800

 
9. Gamez ME, Jeans E, Hinni ML, Moore E, Young G, Ma D, McGee L, Buras MR, Patel SH. Outcomes and patterns of failure of sarcomatoid carcinoma of the larynx: The Mayo Clinic experience. Laryngoscope 2017 Jul 06 Epub 2017 July 06 PMID:28681992   DOI:10.1002/lary.26725