American Head & Neck Society

Advancing Education, Research, and Quality of Care for the Head and Neck oncology patient.

Published on by Snehal Patel

Snehal Patel – New York, New York

Practice Contact Information

Memorial Sloan Kettering Cancer Center
1275 York Avenue
Room C-1076B
New York
New York
10065
United States

Phone: 212-639-3412
Email:
Web Site: https://www.mskcc.org/cancer-care/doctors/snehal-patel

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon

Biography/Statement

Dr. Snehal G. Patel is an Attending Surgeon in the Head and Neck Service at Memorial Sloan Kettering Cancer Center and Professor of Otolaryngology at the Weill Medical College of Cornell University, New York. He went to Medical School in Baroda followed by residency in General Surgery at the SSG Hospital, Baroda, India. He has formal training in head and neck surgical oncology and plastic and reconstructive surgery at the Tata Memorial Hospital (Bombay, India), Royal Marsden Hospital (London) and Memorial Sloan-Kettering Cancer Center (New York).

Dr. Patel has particular expertise in the multidisciplinary treatment of all tumors located in the head and neck area. He is especially interested in minimally invasive treatment with the goal of preserving the patient’s quality of life including the ability to speak and swallow.

Dr. Patel has a special interest in developing novel technology for the treatment of patients with head and neck cancer. The overall goal of his research is to improve outcomes of treatment, patient satisfaction and post-therapy quality of life. He is working to achieve this goal based on a multi-pronged research program that includes development of new technology for in vivo imaging and minimally invasive treatment of tumors, evaluation of patient expectations and development of novel patient education techniques, development of statistical methods for predicting individualized outcomes, and assessment of quality of care, post-therapy patient satisfaction and quality of life. He holds a US patent for a novel image-guided endoscopic laser-surgery device that is currently being developed for minimally invasive surgical applications. His research efforts have been funded by competitive peer-reviewed intra and extramural grants. He is a member of several national and international societies and serves on scientific committees including the American Joint Committee on Cancer Head and Neck Staging Task Force. His clinical research has resulted in over 200 peer-reviewed scientific publications in addition to numerous book chapters and three textbooks on head and neck cancer.

Clinical Trials

 

  1. Targeted Silica Nanoparticles for Real-Time Image-Guided Intraoperative Mapping of Nodal Metastases.
    ClinicalTrials.gov Identifier: NCT02106598
    https://clinicaltrials.gov/ct2/show/NCT02106598?term=NCT02106598&rank=1
  2. A Dye for the Detection of Cancer of the Tongue and Mouth.
    ClinicalTrials.gov Identifier: NCT03085147
    https://clinicaltrials.gov/ct2/show/NCT03085147?term=NCT03085147&rank=1
  3. Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
    https://clinicaltrials.gov/ct2/show/NCT02507141?term=NCT02507141&rank=1

Bibliography

 

Selected publications (out of more than 200 total):

Head and Neck Cancers-Major Changes in the American Joint Committee on Cancer Eighth Edition Cancer Staging Manual.
Lydiatt, William M.; Patel, Snehal G.; O’Sullivan, Brian; et al.
CA-A CANCER JOURNAL FOR CLINICIANS. Mar-Apr 2017 Vol  67, Issue 2. Pages: 122-137.

The recently released eighth edition of the American Joint Committee on Cancer (AJCC) Staging Manual, Head and Neck Section, introduces significant modifications from the prior seventh edition. This article details several of the most significant modifications, and the rationale for the revisions, to alert the reader to evolution of the field.

Significance/Importance
Evidence based analysis was used to create a separate staging algorithm for high-risk human papillomavirus-associated cancer of the oropharynx, distinguishing it from oropharyngeal cancer with other causes. Other modifications include: the reorganizing of skin cancer (other than melanoma and Merkel cell carcinoma) from a general chapter for the entire body to a head and neck-specific cutaneous malignancies chapter; division of cancer of the pharynx into 3 separate chapters; changes to the tumor (T) categories for oral cavity, skin, and nasopharynx; and addition of extranodal cancer extension to lymph node category (N) in all but viral-related cancers and mucosal melanoma.
This article has been cited 21 times since publication in March 2017.
(from Web of Science, Dec 11, 2017).
5-year Impact factor: 160.239 
Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma.
Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG.

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

Extracapsular nodal spread (ECS) has been recognized as a powerful prognostic predictor in head and neck squamous cell carcinoma (SCC). However, an objective definition of clinically relevant ECS was not available.

Significance/Importance
The study showed that ECS is clinically relevant in oral cavity SCC when it has extended more than 1.7 mm beyond the nodal capsule.

This article has been cited 10 times since publication in 2016.
(from Web of Science, Dec 11, 2017).
5-year Impact factor: 3.19
Lymph node density is a significant predictor of outcome in patients with oral cancer.

Gil Z, Carlson DL, Boyle JO, Kraus DH, Shah JP, Shaha AR, Singh B, Wong RJ, Patel SG.
Cancer. 2009 Dec 15;115(24):5700-10.

The impact of lymph node metastases on prognosis in patients with oral cavity squamous cell carcinoma (OSCC) has been well recognized. However, accurate stratification of risk for recurrence among patients with lymph node metastases is difficult based on the existing staging systems. This study evaluated the utility of lymph node density (LND) as an alternative method for predicting survival.

Significance/Importance
This was the first study that reported the use of lymph node density for identifying patients with poor outcomes and this finding was later validated in a larger multi-institutional international study published in 2013.

This article has been cited 82 times since publication in 2009.
(from Web of Science, Dec 11, 2017).
5-year Impact factor: 5.517
The role of pectoralis major muscle flap in salvage total laryngectomy.
Gil Z, Gupta A, Kummer B, Cordeiro PG, Kraus DH, Shah JP, Patel SG. Archives of Otolaryngology-Head & Neck Surgery Oct 2009; 135:1019-1023.

Pharyngocutaneous fistula is a major complication after total laryngectomy and can result in tremendous morbidity and even mortality. The risk of fistula is significantly higher for patients who have had previous radiation or chemoradiation therapy. We showed that the pectoralis major muscle flap is helpful in reducing the sequelae of this major postoperative complication.

Significance/Importance
The report highlighted the utility of a relatively simple vascularized pedicled flap in reducing the risk of a dreaded complication after total laryngectomy.

This article has been cited 53 times since publication in 2009.
(from Web of Science, Dec 11, 2017).
5-year Impact factor: 2.305
Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions.

Bradbury MS, Phillips E, Montero PH, Cheal SM, Stambuk H, Durack JC, Sofocleous CT, Meester RJ, Wiesner U, Patel S.

Integr Biol (Camb). 2013 Jan;5(1):74-86.

 

Sentinel lymph node mapping procedures for detection of melanoma metastases are limited by a lack of intraoperative visualization tools that are capable of accurate determination of disease and discriminating it from adjacent normal critical neural and vascular structures. We have developed a nanoparticle platform with these attributes for image-guided sentinel node identification.

Significance/Importance
This publication was the initial description of our experience in nanoparticle based imaging for melanoma that has recently led to FDA approval and has paved the way for the technology to be trialed in humans.
This article has been cited 56 times since publication in 2013.
(from Web of Science, Dec 11, 2017).
5-year Impact factor: 3.652

Published on by Nabil Saba

Nabil Saba – Atlanta, GA

Practice Contact Information

Winship Cancer Institute, Emory University
1365 Clifton Road
Building C
Atlanta
GA
30322
United States

Phone: 404 778 1900
Email:
Web Site: https://winshipcancer.emory.edu/bios/faculty/saba-nabil.html

Areas of surgical specialization in Head and Neck Surgery

Head and Neck Research, Medical Oncologist

Biography/Statement

Dr. Saba is a Professor in the Department of Hematology and Medical Oncology and is an adjunct Professor of Otolaryngology. He serves as　the Director of the Head and Neck Cancer Oncology Program at the Winship Cancer Institute. His research is focused on basic, clinical and translational research in head and neck malignancies and has focused on advancing the field in these diseases and improving patient outcome through the identification and clinical development of novel therapeutic approaches and correlative biomarkers. Dr Saba is a well-recognized international leader in the field of head and neck cancer clinical research especially in the area of EGFR targeting and immunotherapeutic applications. He has served as the principal investigator of more than 50 interventional and translational clinical trials and is currently serving as PI on two investigator initiated multi-institutional trials in head and neck cancer; Dr Saba is currently the chair of two cooperative group clinical trials in the field of head and neck oncology under the ECOG-ACRIN group; EA3163 is focusing on intensification of therapy for organ preservation in Sino nasal cancers; and EA3161 is investigating a maintenance anti-PD-1 strategy for the intermediate risk oropharyngeal squamous cell carcinomas. He has also received competitive NIH funding through an R21 grant investigating novel genomic approaches in HPV related and unrelated OPCA; Dr Saba is also the recipient of intramural funding and has been the co-Leader of project 4 of the previously funded Emory HNCA SPORE program; He has also received prior funds through the DOD mechanism; As a result of his recognized leadership role in HNCA research Dr Saba has been named the chair of the recurrent metastatic as well as rare tumor Task Forces of the Head and Neck Cancer NCI steering committee; Dr Saba also has more than 150 peer reviewed manuscripts and textbook chapter publications, and is the editor of a textbook updating the management of esophageal cancer;

Clinical Trials

Bibliography

Published on by Joel Fontanarosa

Joel Fontanarosa – Boston, Massachusetts

Practice Contact Information

Mass Eye and Ear / Harvard Medical School
243 Charles Street

Boston
Massachusetts
02114
United States

Phone:
Email:
Web Site:

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Clinical Fellow in Head and Neck Surgical Oncology, Skull Base Surgery, and Microvascular Reconstructive Surgery, Mass Eye and Ear / Harvard Medical School 2018-2019
Residency in Otolaryngology – Head and Neck Surgery, Northwestern University (2018)
M.D., Ph.D. University of Illinois at Chicago
A.B. The University of Chicago

Clinical Trials

Bibliography

Published on by Neerav Goyal

Neerav Goyal – Hummelstown, Pennsylvania

Practice Contact Information

Penn State Milton S. Hershey Medical Center
500 University Drive

Hummelstown
Pennsylvania
17036
United States

Phone: 7175316822
Email: [email protected]
Web Site: https://hmc.pennstatehealth.org/otolaryngology

Areas of surgical specialization in Head and Neck Surgery

Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Neerav Goyal, MD MPH completed his medical school training at Jefferson Medical College followed by a residency in Otolaryngology – Head and Neck Surgery at the Penn State Hershey Medical Center. He also completed a fellowship in Head and Neck Surgical Oncology and Microvascular Reconstructive Surgery at Massachusetts Eye and Ear Infirmary and Harvard Medical School.

His clinical focus and expertise is in the surgical management of patients with head and neck (oral cavity, oropharynx, larynx, paranasal sinuses, neck) cancers, thyroid cancers, salivary gland tumors, and skull base tumors. This interest extends to advocating for and evaluating new technologies to make surgery safer, more efficient, and with better outcomes. To this end, Dr. Goyal has additional training in the use of surgical robots to assist with transoral surgery. He also has a strong focus in the reconstructive management of patients with these diseases through the use of local, regional, or free tissue to help restore form and function.

Dr. Goyal also received a Masters of Public Health from Johns Hopkins University with specific focuses on biostatistics, epidemiology and health economics. His research interests include translational and clinical research of head & neck and thyroid cancers. He also has specific interests in looking at patient reported outcomes as they relate to head and neck cancers.

Dr. Goyal has presented nationally and internationally with more than 30 peer reviewed manuscripts and presentations as well as several book chapters.

Clinical Trials

Bibliography

https://goo.gl/kBUeB7

Published on by Andres Bur

Andres Bur – Kansas City, Kansas

Practice Contact Information

University of Kansas
3901 Rainbow Boulevard
MS 3010
Kansas City
Kansas
66160
United States

Phone: 9135886701
Email: [email protected]
Web Site:

Areas of surgical specialization in Head and Neck Surgery

Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Dr. Bur is an Assistant Professor in the Department of Otolaryngology – Head and Neck Surgery. He completed medical school and residency at the University of Pennsylvania School of Medicine. Dr. Bur then went on to complete a fellowship in Head and Neck Surgical Oncology and Microvascular Reconstruction at Emory University.

His clinical expertise includes the surgical treatment of benign and malignant tumors of the head and neck, including cancers of the mouth, pharynx (throat) and larynx, tumors of the salivary glands, skin including melanoma of the head and neck, thyroid and parathyroid glands. Dr. Bur has specific interests in minimally invasive surgery for cancers of the throat using transoral robotic surgery (TORS) and complex reconstruction of the head and neck using microvascular free tissue transfer techniques.

Dr. Bur is a member of the American Academy of Otolaryngology – Head and Neck Surgery and the American Head and Neck Society. His research interests include patient outcomes after head and neck surgery and microvascular reconstruction, health informatics and quality improvement the quality of care of head and neck patients. Dr. Bur has published numerous peer-reviewed journal articles and has given presentations at regional and national scientific meetings in the field of head and neck surgery.

Dr. Bur obtained his undergraduate degree in Electrical Engineering from Tufts University, where he graduated first in his engineering class and was inducted into Tau Beta Pi and Eta Kappa Nu honor societies. As a medical student, he was awarded as a Clinical and Translational Research Scholar and received training in clinical research methodology at Stanford University. As a fellow at Emory University, Dr. Bur was recognized for going above and beyond in the planning and delivery of patient and family centered care.

Clinical Trials

Bibliography