American Head & Neck Society

Advancing Education, Research, and Quality of Care for the Head and Neck oncology patient.

Published on by Frank Miller

Frank Miller – San Antonio, TX

Practice Contact Information

University of Texas Health Long School of Medicine San Antonio TX
Department of Otolaryngology-HNS

San Antonio
TX
78229
United States

Phone: 210-450-9950
Email: [email protected]
Web Site:

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Professor and Chairman Department of Otolaryngology-Head and Neck Surgery

Director of Head and Neck Oncologic Surgery

Long School of Medicine UT Health San Antonio

Clinical Trials

Bibliography

Published on by Alexandra Kejner

Alexandra Kejner – Lexington, Kentucky

Practice Contact Information

University of Kentucky
800 Rose Street
Markey Cancer Center – Whitney Hendrickson Building
Lexington
Kentucky
40536
United States

Phone: 859-257-4488
Email:
Web Site: https://ukhealthcare.uky.edu/markey-cancer-center/cancer-types/head-neck-cancer

Areas of surgical specialization in Head and Neck Surgery

Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Dr. Kejner is an otorhinolaryngologist/head and neck oncologic surgeon and microvascular reconstructive surgeon.  She is dedicated to the treatment of head and neck patients including those with malignant and benign tumors of the head and neck including skin, sinus, oral cavity, oropharynx, voice box, neck, and salivary glands as well as the reconstruction of those areas after surgery.

She completed her undergraduate degree in Biology and Spanish at Wake Forest University, graduating with honors. From there, she matriculated at the University of Michigan Medical School, where she took part in multiple service activities and graduated with honors in service. She then went on to otorhinolaryngology residency at the University of Alabama – Birmingham before pursuing advanced training in fellowship at the University of Pennsylvania. While there, she received further training in head and neck oncology, skull base surgery, transoral robotic surgery, and microvascular free tissue transfer. She is certified by the American Board of Otolaryngology and has published several articles in peer-reviewed journals as well as several book chapters.

She speaks fluent Spanish. She is interested in medical technology, health care literacy, outcomes research, surgical margins, nutrition and cancer, and head and neck cancer. She has presented at national meetings, has published in peer-reviewed journals, and is a member of the AAO-HNS.

Clinical Trials

Bibliography

Peer-Reviewed Original Research

 

  1. Kejner, A.E.,and Eben L. Rosenthal. Lower facial reanimation techniques following cancer resection and free flap reconstruction. The Laryngoscope 2016, Sept; 126(9):1990-4
  2. Kejner, A.E.,Burch M.B., Sweeny, L., Rosenthal, E.L. Bone morphogenetic protein 6 expression in oral cavity squamous cell cancer is associated with bone invasion. 2013, 123(12):3061-5.
  3. Asher, S.A., White, H.N., Kejner, A.E.,Rosenthal, E.L., Carroll, W.R., Magnuson, J.S. Hemorrhage after transoral robotic-assisted surgery. Otolaryngology – Head Neck Surgery. 2013, 149(1):112-117.
  4. Kejner, A.E.,Castellanos, P.F., Rosenthal, E.L., Hawn, M.T. All-cause mortality after tracheostomy at a tertiary care hospital over a 10-month period.Otolaryngology – Head Neck Surgery. 2012, 146(6):918-922.
  5. Kejner, A.E.,Rosenthal, E.L. Method for removing hypopharyngeal salivary bypass tubes. Laryngoscope. 2011, 121(7):1478-1479.

 

 

Chapters, Books, and Reviews

 

  1. Erman, A.B., Kejner, A.E.,Hogikyna, N.D., Feldman, E.L. Disorders of Cranial Nerves IX and X. Semin Neurol. 2009, 29(1):85-92.
  2. Kejner, A.E.,Woodworth, B.A. Chapter 19: Cystic Fibrosis Sinusitis. Endoscopic Sinus Surgery: Optimizing Outcomes and Avoiding Failures. Schlosser,San Diego, CA, 2011.
  3. Chaaban, M., Kejner, A.E.,Rowe, S.M., Woodworth, B.A. Cystic Fibrosis Chronic Rhinosinusitis: A Comprehensive Review. Am J. Rhinol Allergy. 2013, 27(5):387-95.
  4. Kejner, A.E.,Woodworth, B.A. Chapter 15: Modified Endoscopic Medial Maxillectomy. Sinonasal Surgery, Surgical Techniques in Otolaryngology—Head and Neck Surgery. Singh, Payne, Woodworth, Philadelphia, PA, 2014.
  5. Kejner AE, Newman Jason.  Chapter 44: Tonsillectomy Extended.  Operative Otolaryngology 3rdEdition. 2016 (In submission)

 

Peer-Reviewed Educational Materials

  1. Kejner, A.E.,Woodworth, B.A. Cystic Fibrosis. American Rhinological Society Website, 2011.

Published on by Adam Luginbuhl

Adam Luginbuhl – Philadelphia, Pennsylvania

Practice Contact Information

Thomas Jefferson University
925 Chestnut Street
6th floor
Philadelphia
Pennsylvania
19107
United States

Phone: 215-955-6760
Email: [email protected]
Web Site: http://hospitals.jefferson.edu/find-a-doctor/l/luginbuhl-adam-j.html

Areas of surgical specialization in Head and Neck Surgery

Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Dr. Luginbuhl is at the cutting edge of research bridging the gap of new immunotheraputic options, radioactive isotopes and surgery to offer a broad array of clinical trials and treatment options for head and neck cancer.  His recent work with CDDO compounds in the laboratory have resulted in preventing some of the profound side effects experienced in radiation therapy.

Additionally he is deeply involved in Haitian mission work, taking 3-4 trips/year.  He and his partners have performed the first free tissue transfer and continue to operate regularly in 2 different hospitals.  He is leading a coalition to bring oncologic care to Haiti through radiation and chemotherapy.  https://giving.jefferson.edu/giving/what-to-support/opportunities/complex-head-neck-care-education.html

 

Clinical Trials

Dr. Luginbuhl is the principle investigator on multiple trials including:

  1. Nivolumab +/- Tadalafil Window of Opportunity Trial in Head and neck cancer.  2) Cesium-131 Brachytherapy.

Additional trials involving targeted agents, immunotherapy, radioactive isotopes and metabolic inhibitors.

Bibliography

Published on by Ryan Li

Ryan Li – Portland, Oregon

Practice Contact Information

Oregon Health and Science University
3181 SW Sam Jackson Park Road PV01
Portland
Oregon
97239
United States

Phone: 503-494-5355
Email:
Web Site: https://www.ohsu.edu/providers/ryan-j-li/D11D1B76ECBD43CB8CBA4A8803A5785D

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

Dr. Li specializes in treating head and neck cancers, thyroid and parathyroid diseases, and performing complex reconstructions of head and neck wounds and deformities. He has advanced training in microvascular reconstruction that allows tissues from elsewhere on the body to be transferred to the head and neck where skin, muscle, or bone need to be restored.

Dr. Li is devoted to working alongside patients and their loved ones through their treatments. Together with the multidisciplinary head and neck cancer team, he surrounds patients with gentle, clear and comprehensive care. Dr. Li and the team are dedicated to being patient advocates continually in the years after they complete treatment, to ensure the best quality of life they can achieve.

In his spare time, Dr. Li enjoys the time spent with his wife, Myriam Loyo Li, also a member of the OHSU family, in her role as a facial plastic and reconstructive surgeon. He relishes the company of his extended family spread out over Mexico, Canada, Hong Kong and the eastern United States. Tennis, running, indoor wall climbing and hiking are his hobbies as he enjoys what beautiful Oregon has to offer.

Clinical Trials

Bibliography

Published on by Robert Witt

Robert Witt – Newark, DE

Practice Contact Information

Vanderbilt University Medical Center
4745 Ogletown-Stanton Rd
MAP #1, #112
Newark, DE 19713

 

Phone: 302 738 6014
Email: [email protected]
Web Site: http://www.robertwittmd.com

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon

Biography/Statement

1. Professor: Otolaryngology-Head & Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA
2. Affiliate Professor: Biological Sciences, University of Delaware, Newark DE
3. Director of the Head and Neck Multi-Disciplinary Center, Helen F. Graham Cancer Center, Christiana Care, Newark, DE, USA
4. Principal Investigator (R01 grant)- National Institute of Health (NIH) Grant-
Functional Assembly of Salivary Cells to Relieve Xerostomia
5. Editor of three books (Thyroid Cancer, Salivary Gland Diseases).
6. Authored more than 75 manuscripts and chapters (most as first author)
7. Speaker, panelist, and moderator at many international meetings.
8. Editorial board member of leading journals.
9. Opera and Art Song Tenor Soloist.
10. Fluent in German

Clinical Trials

Bibliography

(1) Schuknecht H, Witt R. Suppressed Sneezing as a Cause of Hearing
Loss and Vertigo. American Journal of Otolaryngology
1985;6:468-470.
(2) Schuknecht H, Witt R. Acute Bilateral Sequential Vestibular
Neuritis. American Journal of Otolaryngology 1985;6:255-
257.
(3) Witt R. Otitis Media: An Overview of Current Treatment
Delaware Medical Journal 1988;60:69-71.
(4) Witt R. The Tonsil and Adenoid Controversy. Delaware Medical
Journal 1989;61:289-293.
(5) Witt R. Management of Adenoid Cystic Carcinoma of the
Minor Salivary Glands. Ear, Nose and Throat Journal
1991;70:218-222.
(6) Witt R. Failure of Radiation Therapy in Stage I and II Glottic
Squamous Cell Carcinoma. Delaware Medical Journal
1995;67:430-435.
(7) Witt R. Primary Small Cell Carcinoma of the Parotid.
Otolaryngology – Head and Neck Surgery 1996;114:826-
829.
(8) Witt R. Facial Nerve Monitoring in Parotid Surgery. Is it the
Standard of Care? Otolaryngology – Head and Neck Surgery
1998;119:468-470.
(9) Witt R. Facial Nerve Function After Partial Superficial
Parotidectomy. Otolaryngology – Head and Neck Surgery
1999;121:210-213.
(10) Witt R. The Significance of Margin in Surgery for Parotid
Pleomorphic Adenoma. Laryngoscope 2002;112:2141-
2154.
(11) Witt R. Prognostic Factors in Mortality and Morbidity in
Differentiated Thyroid Cancer. Ear Nose & Throat
2002;12:856-863.
(12) Witt R. Colonic Adenocarcinoma Metastatic to Thyroid Hurthle Cell
Carcinoma Presenting with Airway Obstruction Del Med J
2003;75:285-288.
(13) Witt R. Sarcoidosis Presenting as Bilateral Vocal Cord Paralysis.
Journal of Voice 2003;2:265-268.
(14) Witt R. Head and Neck Cancer Care in the State of Delaware-The
Advent of the Helen F. Graham Head and Neck Cancer
Center. Delaware Med J 2003;75:455-459.
(15) Witt R. Electrophysiologic Monitoring of the Recurrent Laryngeal
Nerves may not Predict Bilateral Vocal Fold Immobility
after Thyroid Surgery. J Voice 2004;18/2:255-259.
(16) Witt R. A comparison of the results of monolayer versus smear
cytopreparatory techniques for fine-needle aspiration in 100
consecutive patients undergoing thyroidectomy: A surgeon’s
perspective. Otolaryngol Head Neck Surg 2004;131(6):964-67.
(17) Witt R, Weinstein G, Rejto L. Tympanomastoid Suture and
Digastric in Cadaver and Live Parotidectomy. Laryngoscope 2005;115:574- 77.
(18) Witt R. Minimally invasive surgery for parotid pleomorphic
adenoma. ENT J. 2005;84(5):308-11.
(19) Witt R. Electrophysiologic Monitoring in Thyroid Surgery: The
Standard of Care? J Voice. 2005;19(3):497-500.
(20) Witt R. Head and Neck Cancer Care at a Community Based Teaching
Hospital. Head Neck. 2005;27(7):613-5.
(21) Witt R. Gillis G, Pratt R. Spinal accessory nerve monitoring with clinical
outcome measures. ENT J, 2006;85(8):540-544.
(22) Witt R. Comparing the long term outcome of immediate post-operative facial
nerve dysfunction and vocal fold immobility after parotid and thyroid surgery. J Voice. 2006;20(3):461-464.
(23) Witt R., Rejto L. Spinal Accessory Nerve Monitoring in Selective and
Modified Neck Dissection Laryngoscope 2007;117(5):776-780.
(24) Witt R, Rejto L. Pleomorphic adenoma: Extracapsular Dissection versus Partial Superficial Parotidectomy with facial nerve dissection. Del Med J, 2009; 81(3):119-125.
(25) Witt R. Wilson P. Vocal fold immobility from primary minor salivary gland
small cell carcinoma. ENT J 2009;88(2):E13-16.
(26) Witt R, Wilson P Missed opportunity for larynx preservation? Failure to
distinguish verrucous and squamous cell carcinoma on
microlaryngoscopy and biopsy. J Voice 2009;23(1):140-142.
(27) Witt R. Sialendoscopy in Delaware. Del Med J, 2009;81(6)227-29.
(28) Rusthoven KE, Raben D, Schneider C, Witt R, Sammons S, Raben A.
Freedom from local and regional failure of the contralateral neck with
ipsilateral neck radiation therapy for N+ Tonsil Cancer: Results of a prospective management approach. Rad Onc Bio Physics. 2009;74(5):1365-70.
(29) Witt R. The Incidence and Management of Siaolocele Post-Parotidectomy.
Otolaryngol-Head Neck Surg 2009 140,871-74.
(30) Pradhan-Bhatt, S, Zhang C, Jia X, Carson D, Witt R, Farach-Carson MC.
Perlecan domain IV peptide stimulates salivary gland cell assembly in vitro. Tissue Engineering 2009;15(11):3309-3320.
(31) Witt R, Wilson P. Surgery After Cocaine Ingestion. ENT J, 2010;89(2):E14
16.
(32) Swati P, Liu Chao, Zhang C, Jia Xinqiao, Farach-Carson, Witt R. Lumen
formation in 3D cultures of salivary acinar cells. Otolaryngology-Head & Neck Surg 2010;142:195-195
(33) Witt R. What is the treatment of the lateral neck in clinically localized sporadic medullary thyroid cancer Laryngoscope 2010;120(7):1286-87.
(34) Witt R. What is the Best Practice for Benign Mixed Tumor 2011 DE Med J;83(6):175-6.
(35) Witt R. Iro H, Koch M, McGurk M, Nahlieil O, Zenk J. Contemporary Review: Minimally Invasive Options for Salivary Calculi. Laryngoscope 2012;122:1306-1311.
(36) Witt R, Iacocca M. Comparing capsule exposure using extracapsular dissection with partial superficial parotidectomy for pleomorphic adenoma. Amer J Otolaryngol 2012;33(5):581-4.
(37) Zbaren P, Vander Poorten V, Witt RL, et al. Pleomorphic Adenoma of the Parotid: Formal Parotidectomy or Limited Surgery Am J Surg 2013; 205: 109-118.
(38) Witt R, Ferris R, Pribitkin E, Sherman S, Steward D, Nikiforov, Y. Diagnosis and Management of Differentiated Thyroid Cancer using Molecular Biology. Laryngoscope 2013;123:1059-1064.
(39) Witt R, Pribitkin E. How can Frey’s syndrome be prevented or treated following parotid surgery. Laryngoscope 2013;123:1573-74.
(40) Pradhan-Bhatt S, Harrington D, Duncan R, Jia X, Witt R, Farach-Carson C. Implantable Three-Dimensional Salivary Spheroid Assemblies Demonstrate Fluid and Protein Secretory Responses to Neurotransmitters. Tissue Engineering 2013;Vol 19, #13,14, Part A:1610-20. (Cover of Journal, Figure from Journal.)
(41) Lombaert IMA, Abrams SR, Li L. Eswarakumar VP, Sethi AJ, Witt, RL, Hoffman MP. Combined KIT and FGFR2b signaling regulates epithelial progenitor expansion during organogenesis. Stem Cell Reports. 2013;1:604-19.
(42) Pradhan-Bhatt S, Harrington D, Duncan R, Farach-Carson M, Xia J, Witt R. A Novel In Vivo Model for Evaluating Functional Restoration of a Tissue Engineered Salivary Gland Laryngoscope 2014;124:456-61.
(43) Dicker KT, Gurski LA, Pradhan-Bhatt S, Witt RL, Farach-Carson MC, Jia X. Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions. Acta Biomaterilalia. 2014;10:1558-70.
(44) Condamine T, Witt, RL, Gabrilovich I. et al. ER stress response regulates
the fate of myeloid-derived suppressor cells through TRAIL receptors mediated apoptosis in cancer. J Clin Invest. 2014 Jun 2;124(6):2626-39.
(45) Witt RL, Gerges F, Iacocca M. Contemporary Diagnosis and Management of Warthin’s Tumor. De Med J 2014;87(1):13-16.
(46) Witt RL, Eisele D, Morton R. et al. Etiology and Management of Recurrent Parotid Pleomorphic Adenoma. Laryngoscope 2015;125(4):888-893.
(47) Witt RL, Sukumar VR, Gerges F. Surgeon Performed Ultrasound Guided FNAC with On-Site Cytopathology improves adequacy and accuracy. Laryngoscope. 2015;125(7) 1633-6. DOI: 10.1002/lary.25214
(48) Dan TD, Raben A, Witt RL. Freedom from local and regional failure of contralateral neck with ipsilateral neck radiotherapy for node-positive tonsil cancer: Updated results of an institutional clinical management approach. Oral Oncol 2015 doi: 10.1016/j.oraloncology.2015.03.013
(49) Witt RL. Outcome of Thyroid Gene Expression Classifier Testing in Clinical Practice. Laryngoscope. 2016;126:524-27.
(50) Witt, RL. Extracapsular Dissection with Facial Nerve Dissection for Benign Parotid Tumors. Otolaryngology-Head & Neck Surg. 2016;154(3):572-74.
(51) Ozdemir T, Fowler E, Hao Y, Ravikrishnan A, Harrington D, Witt, R, Farach-Carson, M, Pradhan-Bhatt S, Jia X. Biomaterials based strategies for salivary gland tissue regeneration. Biomaterials Science 2016;4:592-604.
(52) Witt RL. What is the Best Management of Incidental Papillary Thyroid Microcarcinoma? Laryngoscope. 2016;126(10) 2203-4.
(53) Srinivasan P, Witt, R, Pradhan-Bhatt, S, et al. Primary Salivary Human Stem/Progenitor Cells (hS/PCs) Undergo Microenvironment Driven Acinar-like Differentiation in Hyaluronate Hydrogel Culture. Stem Cells. 2017;6(1):110-120.

(54) Condamine T, Witt RL, Gabrilovich D. et al. Lectin-type oxidized LDL receptor 1 distinguishes population of human polmorphonuclear myeloid-derived suppressor cells in cancer patients. Science Immunology 2016 1(2):aaf8943
(55) Witt RL, Targeted Next Generation Sequencing with ThyroSeq v2.1 for Indeterminate Thyroid Nodules In Clinical Practice 2016. DE Med J;88(12):366-367.
(56) Tugba O, Fowler E, Witt RL, et al. Tuning Hydrogel Properties to Promote the Assembly of Salivary Gland Spheroids in 3D. ACS Biomaterials Science & Engineering. 2016 12;2(12):2217-2230. DOI: 10.1021/acsbiomaterials.6b00419
(57) Sagiv D, Witt RL, Talmi Y et al . Warthin Tumor within the Superficial Lobe of the Parotid Gland: a Suggested Criterion for Diagnosis. European Arch OtoRhinoLaryngol 2017;274(4):1993-1996.
(58) Roth MY, Witt RL, Steward DL. Molecular Testing for Thyroid Nodules: Review and Current State. Cancer 2018;124(5):888-898. DOI 10.1002/cncr.30708
(59) Witt, RL. Thyroid Molecular Testing using Ultrasound. International Journal of Head and Neck Science 2017;1(3):147-153
(60) Witt RL. Comment on: Does Mutational Analysis Influence the Management of Differentiated Thyroid Cancers? Laryngoscope 2017 DOI: 10.1002/lary.26811
(61) Ozdemir T, Srinivasan PP, Witt RL et al. Bottom-up Assembly of Salivary Gland Microtissues for Assessing Myoepithelial Cell Function. BioMaterials.2017;142:124-135 PMID: 28734180
(62) Witt R. High Thyroid Surgical Volume Compared to Intermediate Volume Reduces Vocal Fold Immobility International Journal of Head and Neck Science (in press)

(63) Condamine T, Dominguez GA, Mony S, Hashimoto A, Liu Q, Forero A, Bendell J, Witt RL, Hockstein N, Kumar P, Gabrilovich DI. Selective targeting of myeloid-derived suppressor cells in cancer patients using DS-8273a, an agonistic TRAIL-R2 antibody. Clinical Cancer Research, 2017 Jun 15;23(12):2942-2950.

(64) Palmer D, Witt RL, Raben, A. et al Combination of post-operative radiotherapy and cetuximab for high-risk cutaneous squamous cell cancer of the head and neck: A propensity score analysis. Oral Oncology 2018 (in press)