American Head & Neck Society

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Published on January 9, 2024 by Marcus Monroe

Marcus Monroe – SALT LAKE CITY, Utah

Practice Contact Information

Huntsman Cancer Institute, University of Utah School of Medicine
50
NORTH MEDICAL DR, SOM 3C-120
SALT LAKE CITY
Utah
84132
United States

Phone:
Email:
Web Site: https://healthcare.utah.edu/find-a-doctor/marcus-m-monroe


Areas of surgical specialization

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery


Biography/Statement

Marcus Monroe, M.D., is an associate professor in the Department of Otolaryngology at the University of Utah School of Medicine. He is a surgeon and investigator with the Huntsman Cancer Institute where he specializes in the complex multidisciplinary care of patients with head and neck cancer.  He serves as the Division Chief for Head and Neck Surgical Oncology within the Department of Otolaryngology, as well as the Physician Lead for the Head and Neck Clinical Trials Program and c0-lead for the Head and Neck Disease Center at the Huntsman Cancer Institute.

Dr. Monroe received his medical degree at the University of Missouri—Columbia School of Medicine and completed his residency training in Otolaryngology—Head and Neck Surgery at Oregon Health and Science University (OHSU) in Portland, Oregon. Prior to joining the faculty at the University of Utah, Dr. Monroe completed a fellowship in Head and Neck Surgical Oncology at the University of Texas M.D. Anderson Cancer Center.

His clinical practice involves treating patients with head and neck melanoma and nonmelanoma skin cancers, thyroid and parathyroid tumors, salivary gland tumors, and cancers of the upper aerodigestive tract (oral cavity, pharynx, larynx, and sinuses). Dr. Monroe believes that the best care comes when a team of specialists works together to create a treatment plan that is tailored to the individual patient. Because of this he works closely with a team of multidisciplinary cancer specialists to determine the best possible treatment for each patient.

Dr. Monroe’s research interests are focused on clinical trials for head and neck cancers, risk stratification for advanced skin cancers, and survivorship issues following head and neck cancer treatment.

Clinical Trials

  • Phase I Study Of Oral LOXO-292 In Patients With Advanced Solid Tumors, Including RET-Fusion Non-Small Cell Lung Cancer, Medullary Thyroid Cancer, And Other Tumors With Increased RET Activity
  • Phase III, Randomized, Double-blind, Placebo-Controlled Study To Evaluate Pembrolizumab Versus Placebo As Adjuvant Therapy Following Surgery And Radiation In Participants With High-Risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
  • Phase I/IB study of DS-8201a in combination with ATR Inhibition (AZD6738) in advanced solid tumors with HER2 expression (DASH Trial)
  • Pembrolizumab in Combination with Dabrafenib and Trametinib as a Neoadjuvant Strategy Prior to Surgery in BRAF-Mutated Anaplastic Thyroid Cancer
  • Randomized Phase II/III Trial of Radiation with High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation with Low-Dose Weekly Cisplatin (40 mb/m2) for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
  • A Randomized, Double-Blind, Multicenter, Phase 2 Study of Retifanlimab in Combination With INCAGN02385 (Anti LAG-3) and INCAGN02390 (Anti TIM-3) as First-Line Treatment in Participants With PD-L1 Positive (CPS 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
  • A Phase I/IIa, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Evidence of Antitumor Activity of JAB-2485 in Adult Patients with Advanced Solid Tumors
  • Phase II Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Naïve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland Cancer
  • Phase 1/2 dose escalation and cohort expansion study evaluating MCLA-158(petosemtamab) as single agent or in combination in advanced solid tumors
  • DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing) a Phase III Trial
  • Open-Label, Randomized, Controlled Multicenter Study of the Efficacy of Daromun Neoadjuvant Intratumoral Treatment Followed by Surgery and Adjuvant Therapy versus Surgery and Adjuvant Therapy in Clinical Stage IIIB/C Melanoma Patients
  • EnergyPoints: A Mobile App Guiding Acupressure Use for Cancer Related Fatigue and Sleep Disturbances
  • Phase I/II Study of an EZH2 Inhibitor (Tazemetostat) in Combination with Dual BRAF/MEK Inhibition in Patients with BRAF-Mutated Metastatic Melanoma Who Progressed On Prior BRAF/MEK Inhibitor Therapy
  • Phase I/IB study of DS-8201a in combination with ATR Inhibition (AZD6738) in advanced solid tumors with HER2 expression (DASH Trial)
  • Pembrolizumab in Combination with Dabrafenib and Trametinib as a Neoadjuvant Strategy Prior to Surgery in BRAF-Mutated Anaplastic Thyroid Cancer
  • Melanoma Margins Trial (MelMarT): A Phase III, Multi-Centre, Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma
  • RISE-UP (Risk Information and Skin-Cancer Education and Undergraduate Prevention) Trial (R01 version)
  • Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination with CMP-001 in Patients with Operable Melanoma: Efficacy and Biomarker Study
  • A Phase I/IIa, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Evidence of Antitumor Activity of JAB-2485 in Adult Patients with Advanced Solid Tumors
  • Phase I Study to Assess the Safety and Efficacy of LYL845 in Adults with Relapsed and/or Refractory Metastatic or Locally Advanced Melanoma and Selected Solid Tumor Malignancies
  • RADVAX: Randomized Phase II Trial Of Ipilimumab And Nivolumab With Or Without Hypofractionated Radiotherapy In Patients With Metastatic Melanoma
  • Phase II/III Randomized Study of Tebentafusp as Monotherapy and in Combination with Pembrolizumab Versus Investigator?s Choice in HLA-A*02:01-positive Participants with Previously Treated Advanced Melanoma (TEBE-AM)
  • Phase I/II, First-in-Human, Open Label, Dose Escalation and Expansion Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients with Unresectable Locally Advanced or Metastatic Cancer

Bibliography

Published on January 3, 2024 by Arielle Thal

Arielle Thal – Philadelphia, Pennsylvania

Practice Contact Information

Thomas Jefferson University
925 Chestnut Street
6th Floor – Otolaryngology Department
Philadelphia
Pennsylvania
19107
United States

Phone:
Email:
Web Site:


Areas of surgical specialization

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery


Biography/Statement

Dr. Arielle Thal completed her residency at Montefiore School of Medicine in the Bronx, NY and her fellowship training in Advanced Head & Neck Oncologic Surgery/Microvascular Reconstruction at Thomas Jefferson University Hospital.  Her advanced training included endoscopic laser techniques, transoral robotic surgery, skull base surgery, and free flap reconstruction.  

Clinical Trials

Bibliography

Published on January 3, 2024 by Denis Kulbakin

Denis Kulbakin – Tomsk, Tomsk region

Practice Contact Information

Tomsk Cancer Research Institute
5 Kooperativny Street

Tomsk
Tomsk region
634009
Russian Federation

Phone: +79069555289
Email: [email protected]
Web Site: https://onco.tnimc.ru/en/


Areas of surgical specialization

Endocrine Surgery, Head and Neck Surgeon, Reconstructive Head & Neck Surgery


Biography/Statement

M.D., Ph.D., D.Sc., Senior Researcher, Department of Head and Neck Tumors, Cancer Research Institute, Tomsk National Research Medical Center.

Denis E. Kulbakin graduated with honors from Siberian Medical University in 2008. From 2008 to 2010 he completed a residency training at the Head and Neck Cancer Department of the Cancer Research Institute of the Tomsk Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences (currently Cancer Research Institute of Tomsk NRMS). In 2013, he defended a doctoral thesis titled «Organ-preserving surgery after radical radiation therapy in patients with recurrent laryngeal cancer» for a Ph.D. degree. From 2016 to 2017, Dr. Kulbakin completed an internship in surgery at the Siberian State Medical University of the Ministry of Health of the Russian Federation. Since 2015, he has been a Senior Researcher at the Department of Head and Neck Cancer of Cancer Research Institute of Tomsk NRMS. In 2021, Dr. Kulbakin defended a doctoral thesis titled “Reconstructive surgery in the combined modality treatment of patients with head and neck tumors. Improving the technique, researching new reconstructive materials” for a D.Sc. degree.

Clinical Trials

Organ-preserving surgery for head and neck tumors using microsurgical reconstruction

Thyroidectomy and parathyroidectomy

Transoral laser microsurgery

Development of new implants for reconstructive surgery in the maxillofacial region.

Bibliography

Spirina Liudmila V. Expression of vascular endothelial growth factor and transcription factors HIF-1, NF-kB expression in squamous cell carcinoma of head and neck; association with proteasome and calpain activities / Spirina Liudmila V., Kondakova Irina V., Choynzonov Evgeny L., Chigevskaya Svetlana Y., Shishkin Dmitry A., Kulbakin Denis E. // J Cancer Res Clin Oncol (2013) 139:625–633

Мukhamedov Мarat. Organ-saving Surgery with the Use of TiNi-based Endografts in Larynx Cancer Patients / Мukhamedov Мarat, Kulbakin Denis, Gynter Victor, Choinzonov Еvgeniy, Checalkin Timofey, Hodorenko // Journal of Surgical Oncology Vol. 111 (2015) pp 231–236.

Choinzonov Еvgeniy. Organ-Preserving Surgery using Endografts from Superelastic Titanium-Nickelid-Based Alloy for Patients with Laryngeal Cancer / Choinzonov Еvgeniy, Мukhamedov Мarat, Kulbakin Denis, Buldakov Mikhail, Gynter Victor // Advanced Materials Research Vol. 1085 (2015) pp 414-418

Denis Kulbakin. Sparing Surgery for the Successful Treatment of Thyroid Papillary Carcinoma Invading the Trachea: A Case Report / Denis Kulbakin, Timofey Chekalkin, Marat Muhamedov, Evgeniy Choynzonov, Ji-hoon Kang, Seung-baik Kang, Victor Gunthera // Case Rep Oncol 2016;9:772–780.    IF – 0,93

Kulbakin Denis. Thyroid Carcinosarcoma // American Journal of Biomedical Science & Research. –  2019. – 5(2). – P. 115-117.

Chernov V.I., Choynzonov E.L., Kulbakin D.E., Obkhodskaya E.V., Obkhodskiy A.V., Popov A.S., Sachkova A.S. and Sachkov V.I. Cancer Diagnosis by Neural Network Analysis of Data from Semiconductor Sensors // Diagnostics 2020, 10(9), 677; https://doi.org/10.3390/diagnostics10090677;

Vladimir I. Chernov, Evgeniy L. Choynzonov, Denis E. Kulbakin, Ekaterina N. Menkova, Elena V. Obkhodskaya, Artem V. Obkhodskiy, Aleksandr S. Popov, Evgeniy O. Rodionov , Victor I. Sachkov, Anna S. Sachkova. Non-Invasive Diagnosis of Malignancies Based on the Analysis of Markers in Exhaled Air. Diagnostics 2020, 10, 934; doi:10.3390/diagnostics10110934

Characterization and Determination of the Biocompatibility of Porous Polytetrafluoroethylene Membranes Fabricated via Electrospinning / I. Kolesnik, T. Tverdokhlebova, N. Danilenko, E. Plotnikov, D. Kulbakin, A. Zheravin, V. Bouznik,  E. Bolbasov // Journal of Fluorine Chemistry. – June 2021. – Vol. 246, N 109798.

Solution blow spinning of PLLA/Hydroxyapatite composite scaffolds for bone tissue engineering / Arnold Popkov, Denis Kulbakin, Dmitry Popkov, Elena Gorbach, Natalia Kononovich, Nadezhda Danilenko, Ksenia Stankevich, Evgeny Choynzonov, Alexander Zheravin, Igor Khlusov, Ludmila Bondar, Vladimir Perelmuter, Evgeny Bolbasov, Sergei Tverdokhlebov // Biomedical Materials. – 2021. – Jul 20. – Vol. 16, N 5.  – doi: 10.1088/1748-605X/ac11ca

E.S. Kolegova, M. R. Patysheva, I. V. Larionova, I. K. Fedorova, D. E. Kulbakin, E. L. Choinzonov, E. V. Denisov: Early-onset oral cancer as a clinical entity: aetiology and pathogenesis. Int. J. Oral Maxillofac. Surg. 2022; 51: 1497–1509. https://doi.org/10.1016/j.ijom.2022.04.005

Anna I. Kozelskaya, Sven Rutkowski, Johannes Frueh, Aleksey S. Gogolev, Sergei G. Chistyakov, Sergey V. Gnedenkov, Sergey L. Sinebryukhov, Andreas Frueh, Vladimir S. Egorkin, Evgeny L. Choynzonov, Mikhail Buldakov, Denis E. Kulbakin, Evgeny N. Bolbasov, Anton P. Gryaznov, Ksenia N. Verzunova, Margarita D. Apostolova and Sergei I. Tverdokhlebov. Surface Modification of Additively Fabricated Titanium-Based Implants by Means of Bioactive Micro-Arc Oxidation Coatings for Bone Replacement. J. Funct. Biomater. 2022, 13, 285. https://doi.org/10.3390/ jfb13040285

I.K. Fedorova, D.E. Kulbakin, E.S. Kolegova, M.R. Patysheva, E.V. Denisov, E.L. Choinzonov, A.P. Polyakov, A.V. Mordovsky, I.V. Rebrikova, A.D. Kaprin, D.A. Averinskaya, M.E. Romanova, P.A. Shatalov, P.V. Shegay, D.S. Kudashkina, L.P. Yakovleva, A.S. Vyalov, M.A. Kropotov, V.T. Tsiklauri, O.A. Saprina, N.S. Sukortseva, S.I. Samoilova, I.V. Reshetov. Treatment of young adults with oral cancer: current state and outlook (The Consortium «Etiology and pathogenesis of oral cancer in young adults»). Part 1. Head and neck. Russian Journal. 2022;10(4):83–91

Vorob’ev, A.O., Kul’bakin, D.E., Chistyakov, S.G.. Mitrichenko A. D., Dubinenko G. E., Akimchenko I. O., Plotnikov E. V., Gogolev A. S., Choinzonov E. L., Buznik V. M., Bol’basov E. N. Individual 3D-Printed Implants Made from a Copolymer of Vinylidene Fluoride with Tetrafluoroethylene: Studies of the Effects of Steam Sterilization on Structure and Toxicity. Biomedical Engineering. 2023; 57: 52–56. –  DOI: 10.1007/s10527-023-10266-y

Naumov S.S., Kulbakin D.E., Krakhmal N.V., Vtorushin S.V. Molecular and biological factors in the prognosis of head and neck squamous cell cancer. Molecular Biology Reports. 2023: Jul 26. – DOI: 10.1007/s11033-023-08611-1 – URL: https://link.springer.com/article/10.1007/s11033-023-08611-1 – PMID: 37493876.

Published on January 1, 2024 by Nicole Fowler

Nicole Fowler – Cleveland, OH

Practice Contact Information

University Hospitals Cleveland Medical Center
11100 Euclid Ave

Cleveland
OH
44106
United States

Phone: 216-844-5460
Email:
Web Site: https://www.uhhospitals.org/doctors/Fowler-Nicole-1134398746


Areas of surgical specialization

Endocrine Surgery, Head and Neck Surgeon, Reconstructive Head & Neck Surgery


Biography/Statement

Nicole M. Fowler, MD FACS is an Associate Professor at University Hospitals Cleveland Medical Center.   She is a Head & Neck Surgical Oncologist and Reconstruction specialist who is driven to provide the best in patient care.  She is the Director of ENT Quality and Patient Safety and is the Head & Neck Fellowship Program Director.  Dr. Fowler’s passion is Head & Neck cancer which includes all areas of the Head & Neck – mouth, nose/sinus, throat, salivary glands, endocrine (thyroid/parathyroids) and skin.  Her expertise includes both ablation and microvascular reconstruction with her focus being complex functional rehabilitation and restoration.

Clinical Trials

Bibliography

Published on December 24, 2023 by Ian Lalich

Ian Lalich – Edina, MN

Practice Contact Information

Renew ENT and Hearing
7300 France Avenue South Suite 420

Edina
MN
55435
United States

Phone: 952-832-5252
Email: [email protected]
Web Site: https://www.renewent.com/


Areas of surgical specialization

Head and Neck Surgeon


Biography/Statement

Dr. Ian Lalich is an otolaryngologist who specializes in head and neck oncology and sleep surgery.  In addition to his work at the clinic, he serves on the board of directors at the Minnesota Academy of Otolaryngology.

Clinical Trials

Bibliography

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