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Published on June 17, 2020 by

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MOC1, MOC2 (Originally from Uppaluri lab)

Investigator NameSilvio Gutkind
Investigator InstitutionUC San Diego, Moores Cancer Center
Lab Contact NameFarhoud Faraji
Lab Contact EmailEmail hidden; Javascript is required.
Lab Contact Phone(916) 508-9300
Histology

Differentiated squamous cell carcinoma

Species

Mus musculus domesticus, C57BL/6

Site of Origin

Oral tongue

Genomic Characteristics

MOC1 - Hras mutation
MOC2 - Kras mutation
MOC22 - Hras mutation

HPV Status

Negative

Established?

Yes

Primary non-immortalized

No

Fluorescence or other transgene status

None, but available with stably transduced GFP-ffLuc (via Addgene #46793 lenti)

Engraftment sites in vivo

Orthotopic

Media Composition

IMDM/F12 (2:1) with 5% fetal calf serum, penicillin/streptomycin, 1% amphotericin, 5 ng/mL EGF (Millipore), 400 ng/mL hydrocortisone, and 5 μg/mL insulin

MTA Required

No

References

https://cancerres.aacrjournals.org/content/72/1/365.full

  • Entry #24336
  • Entry #24335
  • Entry #24333

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AHNS, 11300 W. Olympic Blvd, Suite 600
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